All articles
Evidence-led research on repurposed compounds and the protocols people actually ask about — cited to primary literature and reviewed for accuracy.
New Phase 2 Trial to Test Disulfiram Plus Copper With Radiation in Thoracic Cancer
MD Anderson registered a Phase 2 trial of disulfiram plus copper gluconate with radiotherapy in thoracic cancer, aiming to trigger cuproptosis; not yet recruiting.
Statins Drain a Battery Cancer Cells Need — and Expose a Weakness, Study Finds
Statins drain the NAD+ battery cancer cells use to make serine; in neuroblastoma models, adding a serine-blocking drug to simvastatin increased anti-tumor activity in mice.
Metformin May Reverse Hormone-Drug Resistance in Prostate Cancer, Lab Study Finds
Prostate tumors dodge a cell-death pathway using the GSTA4 protein; metformin blocked it and re-sensitized tumors to hormone-blocking drugs in cell and animal models.
Arctigenin and Curcumin Combination Induces Redox Stress and Apoptosis in Prostate Cancer Cells: Nutrients 2026
A September 2026 Nutrients study demonstrates that combining arctigenin with curcumin produces synergistic redox stress, AMPK activation, and apoptosis in PC-3 prostate cancer cells, with marked selectivity over normal prostate epithelial cells.
DNA Nanorobot Carries Methylene Blue Deep Into Tumors: 85% Regression in Mice
A self-propelled DNA nanorobot delivered methylene blue deep into oxygen-starved tumors, producing 85% tumor regression in mice via enhanced photodynamic therapy.
Metformin-Loaded Nano-Carriers Boost Immunotherapy in Triple-Negative Breast Cancer — Mouse Study
In mice with triple-negative breast cancer, microscopic carriers loaded with metformin plus an immune-boosting compound shrank tumors, reduced spread and extended survival.
Statins May Prime the Immune System Against Ovarian Cancer, New Preprint Suggests
Preprint (not peer-reviewed): daily statin use is linked to longer survival in ovarian cancer, and atorvastatin activated cancer-killing immune cells in mice with ovarian tumors.
Mebendazole Suppresses Colorectal Tumors with Low PNLDC1 Levels, Preclinical Study Finds
Laboratory study: colorectal tumors low in the PNLDC1 protein grow more aggressively — and the antiparasitic drug mebendazole curbed that excess growth in cancer cells, in mice, and in tumor samples taken from patients. No patients were treated.
Metformin Use Linked to Lower Bladder Cancer Risk: Meta-Analysis of 6.3 Million People with Diabetes
A review of 14 studies covering ~6.3 million people with type 2 diabetes: metformin users developed bladder cancer about one-third less often; pioglitazone and SGLT2 inhibitors showed no clear link.
Fenbendazole
Fenbendazole for Cervical and Blood Cancers
Preclinical evidence for fenbendazole in cervical cancer (HeLa) and blood cancers (leukemia and lymphoma), with honest limits and real PubMed sources.
Fenbendazole
Fenbendazole for Bladder Cancer: Research Review 2026
Preclinical research on fenbendazole for bladder cancer: the 2026 photothermal ferroptosis nanoplatform study, mechanisms, and honest evidence limits.
Ivermectin Blocks Stress Granule Clearance in Neuroblastoma Cancer via Hsp70 Inhibition
New 2026 research in Cells shows ivermectin prevents stress granule dissolution in neuroblastoma cells by suppressing de novo Hsp70 protein synthesis, revealing a novel anticancer mechanism.
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